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How do steroids work? Steroids work by decreasing inflammation and reducing the activity of the immune system. Inflammation is a process in which the body's white blood cells and chemicals can protect against infection and foreign substances such as bacteria and viruses. In certain diseases, however, the body's defense system (immune system) doesn't function .

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Oct 09,  · BY Devon Carter. Steroids are a natural part of your body. They’re hormones that help regulate your body’s reaction to infection or injury, the speed of your metabolism and more. In medicine, we can use artificial steroids called corticosteroids to help break fevers, bring down inflammation and reduce pain.